Life science laboratories are increasingly embracing the idea of moving into high-rise settings in city centers, filling space in new construction, or renovating office space left vacant, in part, by the many companies opting to continue to work from home following the pandemic. High-rise laboratories in urban settings offer many advantages related to recruiting top talent, the ease of city amenities, and abundant transportation options, says Matthew Decker, AIA, architect for CRB in Plymouth Meeting, Penn. But they also pose challenges, including strict building codes for hazardous materials, and infrastructure concerns that can affect placement of lab equipment, HVAC systems, and utilities.