Biocontainment

Texas Biomedical Research Institute (Texas Biomed), home to North America’s largest baboon population dedicated to research, has opened a new primate research facility focused on animal welfare, human safety, and operational efficiency as guiding principles. The new Animal Care Complex (ACC) includes three modular breeding and holding facilities, each with a capacity of up to 300 animals of multiple species. The spacious facility has five indoor rooms which range from 400 to 800 sf, and outdoor yards as big as 5,500 sf. 

Allentown, a premier provider of animal housing solutions, is partnering with The Jackson Laboratory (JAX) to launch a revolutionary home-cage mouse monitoring system powered by AI and machine learning (ML). This strategic collaboration is designed to accelerate preclinical research and improve the translatability of preclinical readouts to clinical applications.

MilliporeSigma, a subsidiary of Merck KGaA, opened a $317.2 million facility in Rockville in October of 2024. Located in the Alexandria Center at Traville Gateway, the 260,000-sf building provides advanced laboratories for biosafety testing, analytical development, viral clearance, and cell bank manufacturing. The project represents the company's largest investment to date in contract testing operations.

Texas Tech University opened the $112.5 million Academic Sciences Building in Lubbock in August of 2024. Enhancing the student experience with new venues for active learning and exchange, the 130,000-sf facility was designed by BGK Architects and EYP Architecture & Engineering (now a Page company). The three-story structure provides teaching and laboratory space for five departments: chemistry and biochemistry, physics and astronomy, biological sciences, geosciences, and psychological sciences.

The State of Missouri broke ground in June of 2024 on a $151 million project that will collocate five agencies in one integrated location. Designed by Multistudio, the 208,000-sf facility will provide laboratories and support spaces for the departments of agriculture, natural resources, conservation, and health and senior services, as well as the Missouri State Highway Patrol. This centralized hub will enhance operational efficiencies by creating an ecosystem of resources that will optimize the delivery of analytical services.

The University of Southern California is planning to break ground in late 2024 on the $315 million Discovery and Translational Hub on its Health Sciences Campus in Los Angeles. Designed by SmithGroup, the seven-story, 250,000-gsf building will provide advanced biomedical research environments in a ratio of 75 percent wet lab to 25 percent dry lab. Sited atop two additional levels of subterranean shell space, the 150,00-asf facility will include collaboration areas, offices, meeting venues, a biorepository, and a core lab for medicinal chemistry.

The University of Louisiana at Lafayette began construction in June of 2024 on a significant expansion of the New Iberia Research Center, the nation's largest facility for nonhuman primates. Creating an onsite BSL-3 laboratory for the study of infectious diseases and select agents, the $25 million project will enable the development of novel vaccines, diagnostics, and mitigation solutions. Paul J.

WACKER opened the mRNA Competence Center in June of 2024 in Halle an der Saale, Germany. Representing an investment of over €100 million, the next-generation facility enables the large-scale production of active ingredients based on messenger ribonucleic acid (mRNA). The building spans a total floor area of 79,653 sf and accommodates four new lines supported by advanced infrastructure, including 17,222 sf of glass-enclosed cleanroom space for bioprocessing under controlled conditions. 

Cincinnati Children’s Hospital Medical Center began construction in June of 2024 on the Applied Gene and Cell Therapy Center in Sharonville, Ohio. The $60 million project will transform an existing structure into a catalyst for innovative clinical trials. Designed by BHDP Architecture, the 111,000-sf facility will advance the development, testing, and manufacture of new medicines and biological therapies.

Sanofi opened a 20,000-sf biomanufacturing center in May of 2024 in Toronto. Producing adult and pediatric vaccines for pertussis, diphtheria, and tetanus, the project significantly increases capacity to meet growing demand in Canada and around the world. The next-generation facility features advanced bioprocessing suites supported by highly efficient infrastructure. Commissioning is currently under way, with full operations slated to commence in mid-2025.

The U.S. Department of Agriculture broke ground in May of 2024 on the $160 million National Center for Resilient and Regenerative Precision Agriculture (NCRRPA). Created in partnership with the University of Nebraska–Lincoln, the transformative development will enable the Agricultural Research Service to explore new solutions for sustainable crop production, water management, and animal husbandry.

Many Veterinary Diagnostic Laboratories face operational challenges stemming from their aging facilities, which can jeopardize the biosafety and biosecurity of their environment and hinder testing efficacy and turnaround times. Key strategies to modernizing these facilities include evaluating and improving sample receiving protocols and personnel/material circulation, as well as spatial planning and process optimization of the necropsy operation. These steps are aimed at improving the efficacy and efficiency of diagnostic services; achieving necessary biosecurity and biosafety standards; and attaining accreditation from the American Association of Veterinary Laboratory Diagnosticians and the National Animal Health Laboratory Network. 

The International Society for Pharmaceutical Engineering (ISPE) has announced the 2024 Facility of the Year Awards category winners. The awards include:

Increasing demand for BSL-3 and ABSL-3 lab space in the wake of the COVID-19 pandemic is driving up interest in renovating existing research facilities to accommodate these high-containment spaces. Even a small BSL-3 lab can be a costly undertaking, with special attention required for security of both personnel and biohazards, location in the building, and waste disposal, as well as the design and commissioning of exhaust system.

Texas A&M University is constructing the $49.9 million Nursing Education and Research Building in McAllen. Designed by Page, the three-story, 61,000-sf facility will address a crucial need for skilled healthcare professionals by improving access to learning opportunities in the Rio Grande Valley. The flexible, technology-enabled structure will provide a 10,000-sf clinical simulation center, four nursing classrooms, and areas for informal interaction and study.