How did the Massachusetts Institute of Technology (MIT) convert two century-old industrial buildings -- a former Model T Ford assembly line and the manufacturing plant where the instant camera was invented for Polaroid -- into Class A research space? They accomplished it for the same cost as new construction but in less time, with a much smaller carbon footprint, and the blessing of their neighbors.
AstraZeneca opened a $300 million cell therapy facility in May of 2025 in Rockville, Md. Developed by Alexandria Real Estate Equites, the 84,264-rsf building features specialized environments for the production of chimeric antigen receptor therapies (CAR-T) and T-cell receptor therapies (TCR-T). Next-generation biomanufacturing suites will leverage advanced process controls to create life-saving personalized medicine treatments, spanning every step from culturing and formulation to testing.
As institutions aim to reduce both operational and embodied carbon emissions, laboratory designers can pursue this goal by specifying low-carbon materials and implementing new energy solutions during design and construction, as well as considering the building’s ongoing maintenance. Operational carbon is the carbon that is emitted to run the building over its lifetime. Embodied carbon is the carbon that is emitted in the extraction, manufacturing, and transportation, installation, maintenance, and disposal of materials used during the construction of the building.
Simmons University is partnering with Skanska to create Longwood Place, a vibrant nexus for research, work, and community engagement in Boston. Featuring 2.6 acres of public space, the mixed-use project will leverage sophisticated amenities to transform the district into a destination for economic growth and innovation. The redevelopment of the university’s residential campus in Fenway will provide over 1.3 million sf of Class A lab and office environments, retail and community venues, and approximately 380 housing units.
McGill University is nearing the end of a 10-year project to construct 500,000 sf of research and teaching space on the site of a century-old hospital. The heritage wings of the former hospital will be rehabilitated, and state-of-the-art research and teaching functions will be accommodated in the new construction that is carefully inserted into the site. Renovated space totals 150,000 sf, with 380,000 sf of new construction. Construction is under way, and the building is set for completion in 2028, at a cost of $870 million (Canadian).
Denver University is planning to construct the STEM Horizons building to expand and accelerate vital research in science, technology, engineering, and mathematics. Designed by Anderson Mason Dale with Research Facilities Design (RFD) as laboratory design consultant, the six-story structure will provide 87,000 sf of new and renovated space for hands-on learning, research, business incubation, and community partnerships.
The new Research Building IV (RB4) at Nationwide Children’s Hospital (NCH) in Columbus, Ohio, provides an ideal environment for productivity, collaboration, and flexibility by using a space policy to maximize the efficient use of labs and ancillary spaces; a neighborhood floor plan; and shared resources. The 290,000-sf building, which opened in May 2023 as part of NCH’s Abigail Wexner Research Institute (AWRI), aligns with the hospital’s “one team” culture by providing opportunities for scientists to collaborate, propelling pediatric research forward and closing the gap between lab research and bedside care.
Though universities may update master plans every five or 10 years, many find planning works best when it is continual and flexible to accommodate program and leadership changes. A number of projects at the University of North Texas Health Science Center (HSC) in Fort Worth demonstrate the need to assess existing spaces and develop plans for growth and flexibility, as well as the benefits of building long-term relationships with architects and other vendors.
The 2024 SEFA Lab of the Year was awarded to the new Roche Pharma Research and Early Development (pRED) Center in Basel, Switzerland, that opened in September 2024 as a state-of-the-art research center dedicated to the discovery and development of groundbreaking drugs. The pRED Center exemplifies the future of transformative research by fostering innovation and collaboration, and embodying Roche’s commitment to advancing global healthcare and delivering life-changing treatments.
The Wisconsin Department of Justice (DOJ) is creating a new $115.5 million facility for the Milwaukee Crime Lab in partnership with the Medical College of Wisconsin to drive discovery, innovation, and education in the forensic sciences. Replacing the existing complex, the 73,188-gsf project will include 64,802 gsf of shared space that will also accommodate operations for the Division of Forensic Sciences. The center will also offer training spaces, offices, and a parking garage.
An evolution of the equipment and technology researchers need is transforming ordinary labs into facilities that deserve to be called next-generation or future-ready. Significant changes in space utilization and lab planning and design are driven by increased automation and robotics, the incorporation of manufacturing, enhanced information technology with an emphasis on data collection, ever-evolving technologies, developer core/shell fit-outs, hybrid work patterns, and different approaches to project delivery and construction.
Sutter Health will establish a 12-acre medical campus in Emeryville as part of a $1 billion investment to enhance the delivery of integrated care throughout the East Bay region. The 1.3 million-sf project includes the adaptive reuse of BioMed Realty’s Emery Yards development to create a 530,000-sf outpatient complex spanning two existing structures.
The successful decarbonization of labs and other critical science environments to increase energy efficiency, occupant safety, and annual savings requires a goal-oriented project team with the cultural mindset to adopt effectual technology/engineering processes, procurement strategies, and incentive-based outcomes. Science and engineering facilities often encounter substantial obstacles, such as cost restraints, safety issues, restrictive regulations, and tight deadlines, when completing the massive energy transition necessary to decarbonize their labs.
BioMed Realty is constructing a 637,000-sf life sciences facility in Cambridge for Takeda Pharmaceuticals. Designed by CBT Architects, the 16-story structure will provide advanced lab and office environments to accelerate the creation of innovative therapies and vaccines. Featuring flexible spaces to optimize in-person interaction and connection in a hybrid working model, the leased building furthers Takeda’s goal of unifying their Global R&D Center in Kendall Square.
The Dr. Allen and Charlotte Ginsburg Center for Quantum Precision Measurement at Caltech in Pasadena will house sections of the physics department in subterranean labs filled with specialized space for experimentalists who require unique instrumentation with stringent specifications, which in large part drove the design of the facility. The four upper levels of the new 70,000-sf facility will include multipurpose space for seminars, lectures, and special events; and office workspace for theoretical physicists.
