Biomedical

Novo Nordisk has executed a long-term, full-building lease for a 165,940-rsf property at the Alexandria Center for Life Science in Waltham, Mass. Located at 60 Sylvan Road, the research facility is being redeveloped to provide next-generation environments for biomedical discovery. Neighborhoods of labs, offices, and collaboration spaces will foster interaction between investigators to accelerate the discovery and commercialization of new therapies. Occupancy is expected in 2025.

The use of animals in biomedical research, already a decades-long ethically charged issue, has come under fire in more recent years for both a lack of scientific rigor and its huge financial appetite. Concerns about waste in basic research—in animal lives, scientist time, and research costs—are mounting, particularly when investigators are unable to confirm the data and achieve the same results when replicating original experiments (either theirs or others’). The solution? Track the effects of extrinsic environmental factors that can impact an animal's behavior, health, and reproduction: temperature, humidity, light, noise, and vibration.

Lonza is investing $1.2 billion to purchase a pharmaceutical manufacturing campus in Vacaville, Calif. Presently occupied by Genentech, a subsidiary of Roche, the 427,000-sf complex provides a total bioreactor capacity of approximately 330 liters. Lonza is offering employment to 750 personnel at the site, which will continue to supply its current products at a committed volume of 30 percent throughout 2025.

Pfizer has signed a 15-year lease for 230,000 sf of Class A research space in San Diego to accommodate its growing oncology division. The global pharmaceutical manufacturer will occupy two of the three buildings that are currently under construction at Breakthrough Properties' Torrey View campus. Leading-edge wet labs will advance the creation of novel therapies, accompanied by flexible offices and collaboration spaces.

Phase 3 Real Estate Partners and Bain Capital completed construction in February of 2024 on Genesis Marina, a waterfront life sciences campus in Brisbane, Calif. Offering floor plates of up to 42,000 sf, the three-building complex provides over 560,000 rsf of Class A laboratory and office space. Every research suite is equipped with a modular benching system that is pre-plumbed and pre-wired for fast installation and effortless reconfiguration.

Oxford Properties is transforming Victoria House in central London into a vibrant destination for biomedical research. Developed in partnership with Pioneer Group, the £70 million project involves the conversion of 220,000 sf of the building's 300,000-sf internal area to provide sophisticated wet labs and write-up areas.

The Ingham Institute for Applied Medical Research broke ground in February of 2024 on the AU$55 million Lang AO Medical Research Building - MacArthur. Located next to Campbelltown Hospital, the 63,000-sf project will provide state-of-the-art laboratories for the study of diabetes, pediatrics, addiction, mental illness, and indigenous health, and pediatrics. BVN Architecture’s vision for the translational facility interweaves collaboration spaces and instrumentation suites with flexible, open settings for shared discovery.

Increasing demand for BSL-3 and ABSL-3 lab space in the wake of the COVID-19 pandemic is driving up interest in renovating existing research facilities to accommodate these high-containment spaces. Even a small BSL-3 lab can be a costly undertaking, with special attention required for security of both personnel and biohazards, location in the building, and waste disposal, as well as the design and commissioning of exhaust system.

Beacon Capital Partners and Trammell Crow Company are constructing Hyde Park Labs in Chicago. Designed by Elkus Manfredi Architects, Moody Nolan, and Interactive Design Architects (IDEA), the $225 million project involves the creation of a 13-story building atop an existing retail podium. The completed 370,000-sf facility will offer 300,000 rsf of Class A lab and office space spread over nine floors.

Kadans Science Partner is planning to construct a 139,000-sf research facility in Cambridge in the United Kingdom. Featuring a modular layout that can accommodate multiple tenants or a single entity, Merlin Place will provide best-in-class lab environments for the creation of new therapies, medical devices, and digital healthcare solutions. A flexible structural grid with adaptable floor heights will support a range of configurations, with vibration-mitigated suites available for sensitive instrumentation.

Regeneron Pharmaceuticals is planning to establish a biomedical research facility in Suffern, N.Y. The company recently invested $39 million to acquire the 235,000-sf Avon Innovation Center. Sited on 10 acres, the three-story structure originally housed chemistry labs and support spaces for the development of cosmetics, fragrances, and skincare products. HLW designed the facility, which was constructed between 2003 and 2005 by Skanska USA Building.

Providence Health Care is planning to construct the CAD$638 million Clinical Support and Research Centre in Vancouver. Designed by Diamond Schmitt Architects and Kirsten Reite Architecture, the 370,000-sf facility will collocate world-class research labs with specialty physician practices to accelerate the translation of medical discoveries into solutions for patient care. Collaboration spaces will be intentionally woven throughout the building to promote interdisciplinary exchange between researchers, clinicians, and industry partners.

AstraZeneca is investing $300 million to establish a cell therapy manufacturing facility in Rockville, Md. Developed by Alexandria Real Estate Equites, the Class A+ property is located in the vibrant innovation ecosystem of the Alexandria Center for Life Science at Shady Grove. AstraZeneca has executed a 13-year lease for the entire 84,264-rsf building.

The University of California, Irvine is constructing the $250 million Falling Leaves Foundation Medical Innovation Building to accelerate the discovery of new modalities for disease prevention, diagnosis, and treatment. Designed by LMN Architects, the 215,000-sf structure will provide advanced wet labs where teams of investigators will engage in cross-disciplinary research. Featuring integrated collaboration venues and support spaces, the project will also include offices, meeting rooms, and a vivarium.

Alexandria Real Estate Equities opened a 215,000-sf life sciences center in early 2024 in San Francisco’s Mission Bay district. Designed by IwamotoScott Architecture in association with DGA and Powell Architecture, the seven-story building provides 133,000 sf of Class A lab space, 50,000 sf of office space, and 2,600 sf of ground-level retail.