Genomics

The University of Virginia is constructing the $350 million Paul and Diane Manning Institute for Biotechnology in Charlottesville to catalyze breakthroughs in the fields of cellular therapy, gene therapy, nanotechnology, and drug delivery. Designed by Elkus Manfredi Architects, the flexible building will provide 355,809 sf of space for leading-edge laboratories, core facilities, advanced manufacturing suites, and clinical environments.

The University of Alabama at Birmingham opened the Altec/Styslinger Genomic Medicine and Data Sciences Building in October of 2025. Designed by William Blackstock Architects, the $78 million project involved the renovation and expansion of the existing Lyons-Harrison Research Building to accommodate leading-edge labs, computational suites, meeting rooms, offices, and purpose-built venues for innovation and collaboration.

Ancora L&G opened a $165 million life sciences center in October of 2025 in Providence, Rhode Island. Located in the city’s I-95 innovation district, the 212,000-sf building accommodates 80,000 sf of world-class research space owned by and dedicated to the Rhode Island Department of Health.

More and more universities are building their scientific research centers around cores of huge, heavy, yet surprisingly delicate equipment. Building a core laboratory facility forces architects and campus planners to think about logistics, timing, and backup systems to a level of detail probably more familiar to NASA engineers than institutional architects. As the team behind Emory University’s new Health Sciences Research Building II (HSRB-II) learned, a huge range of factors—in their case, everything from the amount of rebar in the flooring to the width of the corridors to shipping velocity on the Suez Canal—must be reckoned with before such a facility is completed.

Claremont McKenna College opened the Robert Day Sciences Center in September of 2025 in Claremont, Calif. As the home for the new Kravis Department of Integrated Sciences, the 135,000-sf facility enables a transformative pedagogy organized around three overlapping foci: health, brain, and planet. The three-story structure supports a research-centered, solutions-driven curriculum, creating experiential learning opportunities for students and emphasizing the applications of artificial intelligence to real-world challenges.

The University of Pittsburgh is constructing the state-of-the-art BioForge center in the Hazelwood Green development, a brownfield site site that once accommodated a steel mill. Designed by HOK, the $250 million hub will drive breakthroughs and innovations in the manufacturing of precision biological medicines to improve human health. The 185,000-sf building will fill a critical gap in the local biotechnology ecosystem by addressing production constraints and cost-based obstacles to the wide distribution and accessibility of novel treatments.

The University of California, Berkeley is planning to begin construction in spring of 2026 on a seven-story facility for the Innovative Genomics Institute and Bakar Labs. Designed by DGA and Weiss/Manfredi, the development will expand research capabilities in genomics engineering with CRISPR technologies and provide critical infrastructure for life science companies scaling their operations. 

Construction will begin in fall of 2025 on the first phase of a 1,614,600-sf expansion of the Wellcome Genome Campus in the Hinxton, Cambridgeshire. The transformative project is led by master developer Urban&Civic and will extend the site from 125 to 440 acres. Supported by infrastructure works including roads, bridges, and utility networks, this visionary initiative will also deliver 1,500 homes, a recreation center, a swimming pool, and other amenities.

An evolution of the equipment and technology researchers need is transforming ordinary labs into facilities that deserve to be called next-generation or future-ready. Significant changes in space utilization and lab planning and design are driven by increased automation and robotics, the incorporation of manufacturing, enhanced information technology with an emphasis on data collection, ever-evolving technologies, developer core/shell fit-outs, hybrid work patterns, and different approaches to project delivery and construction. 

The vision of biomedical research as a collective effort is resoundingly clear in the $237.5 million Pelotonia Research Center, the first building to be completed in the 350-plus-acre Carmenton district on the campus of The Ohio State University (Ohio State) in Columbus. Opened in May 2023, the center integrates almost 100,000 sf of wet labs, 25,000 sf of computational labs, and 20,000 sf of core labs in a single facility designed to host interdisciplinary collaborations and public-private initiatives that focus on solving some of the most critical health challenges. With life science as the backbone of the research endeavor, current projects range from modeling cancer progressions to 3D printing of patient-specific anatomic models. 

The Sam and Ann Barshop Institute for Longevity and Aging Studies at the University of Texas Health in San Antonio illustrates the pivotal role location plays in enhancing the success of an internationally recognized research program. The Institute previously occupied two buildings at a research park 23 miles from the university’s main campus. University administrators wanted to collocate all research on the same campus to promote multidisciplinary collaboration and interaction, with proximity to all clinical research activities, and to promote efficiency and the shared use of resources. 

The University of Massachusetts Chan Medical School opened the $325 million New Education and Research Building in June of 2024 in Worcester. ZGF Architects and ARC/Architectural Resources Cambridge designed the 350,000-sf project to drive discovery in gene therapy, molecular medicine, and the neurosciences, as well as housing the departments of neurology and neurobiology.

Columbia University broke ground in late May of 2024 on the first all-electric biomedical research building in New York City. Designed by KPF, the 77,000-sf facility will drive innovation in genetic and genomic science to create new treatments for some of the most significant threats to human health today. The eight-story structure will feature state-of-the-art laboratories linked by "collaboration corners" with welcoming lounges for informal interaction and exchange.

The use of animals in biomedical research, already a decades-long ethically charged issue, has come under fire in more recent years for both a lack of scientific rigor and its huge financial appetite. Concerns about waste in basic research—in animal lives, scientist time, and research costs—are mounting, particularly when investigators are unable to confirm the data and achieve the same results when replicating original experiments (either theirs or others’). The solution? Track the effects of extrinsic environmental factors that can impact an animal's behavior, health, and reproduction: temperature, humidity, light, noise, and vibration.

Imperial College London opened the £120 million Laboratory of Medical Sciences in January of 2024 on the Hammersmith Hospital Campus. Designed by Hawkins\Brown to support team science, this collaborative hub for translational research accommodates programs in genetics, sex-based disease differences, and heart and metabolic disorders. The 130,000-sf structure features highly controlled lab environments carefully interwoven with comfortable write-up spaces and shared amenities.