Biomedical

The Centers for Disease Control and Prevention (CDC) will begin construction in early 2021 on the 160,000-sf High Containment Continuity Laboratory in Atlanta. Designed by a joint venture of Flad Architects and Page, the BSL-4 facility will support the CDC's mission to rapidly detect and mitigate public health hazards. Accommodating approximately 80 investigators, the state-of-the-art laboratory will be one of three centers in the world designed and certified to facilitate diagnostic research on specific, select viruses.

The University of Hawaii at Manoa completed construction in June of 2020 on the $65 million Life Sciences Building in Honolulu. Accommodating the College of Natural Sciences' School of Life Sciences, the 70,000-sf interdisciplinary facility offers six teaching labs, 15 research labs, 28 faculty offices, 52 graduate student workstations, five conference rooms, and a 600-sf student collaboration area.

Trammell Crow Company will break ground in July of 2020 on Fulton Labs in Chicago. Providing wet and dry research environments, the 16-story, 423,454-sf life science facility will offer column-free and long-span layouts as well as a dedicated innovation floor for early-stage companies. Designed for maximum flexibility and scalability, the 16-story structure will integrate advanced mechanical infrastructure to support advanced R&D enterprises, with all labs meeting VC-A vibration criteria to ensure reproducible research results.

Sanofi Pasteur is planning to create the Evolutive Vaccine Facility (EVF) in Neuville sur Saône, France. Representing an investment of €490 million over a five-year period, the structure will house a central unit containing several fully digital production modules, enabling the manufacture of four vaccines simultaneously. This modularity will make it possible to prioritize the delivery of a specific vaccine to address crucial public health issues. The company will also invest €120 million to construct a new R&D center in Marcy-l'Etoile.

AZIsotopes is building a $45 million headquarters and production facility in Bunker Hill, Ind. The project includes the renovation of a 55,000-sf shell building and the construction of a 28,000-sf addtion, which will house a cyclotron vault with walls ten feet thick to isolate the instrument's two 70-ton magnets. Strategically located near Grissom Air Force Base to meet security requirements, the facility will support the creation of medical isotopes for diagnostic testing and clinical treatment. Operations at the site are expected to begin by early 2021.

Access to quick, reliable, and repeated testing has been one of the greatest challenges for businesses, institutions, and individuals during the SARS-CoV-2 crisis. HOK has partnered with Germfree Laboratories to design a mobile testing lab that will help large organizations to meet this urgent need. These self-contained biocontainment facilities can provide advanced, onsite capabilities for any setting.

The South Australian Health and Medical Research Institute will begin construction in July of 2020 on the SAHMRI 2 building in Adelaide. Designed by Woods Bagot, the AUD$500 million project will accelerate the delivery of leading-edge clinical care as well as accommodating growing research programs in health analytics, artificial intelligence, and machine learning. Standing 12 stories above grade with three underground levels, the facility will house the Australian Bragg Centre for Proton Therapy & Research and the SAiGEN Cancer Institute.

Amid sobering reports of job losses in commercial real estate, coupled with months-long construction shutdowns in major markets like Boston and New York, the life sciences sector is poised to experience a less dramatic disruption, and possibly emerge from the pandemic even stronger than it was before. “COVID is a healthcare crisis, so it needs a healthcare solution, and that life sciences and biophparma solution has to be constructed,” says Kevin Chronley, vice president of A/Z Corp. and immediate past president of the Boston Area Chapter of International Society for Pharmaceutical Engineering (ISPE). Chronley predicts that construction will run the gamut from medical device manufacturing and biopharma laboratories to education and training facilities.

Ryvu Therapeutics completed construction in June of 2020 on the R&D Center for Innovative Drugs in Krakow, Poland. Accommodating approximately 300 employees, the $20 million headquarters and research facility will enable the clinical-stage biopharmaceutical company to accelerate the development of novel small molecule therapies that address emerging targets in oncology.

Genomic Partnership Wales is planning to construct a research facility in Cardiff in the United Kingdom to accelerate the development of pharmaceutical therapies. Created by a consortium of government, academic, and medical partners, the project involves the redevelopment of an existing two-story building to provide leading-edge genetics labs, seminar rooms, treatment suites, offices, freezer rooms, and support. The facility will include CL2 biocontainment research suites to ensure compliance with the UK's HBN 15 regulations for pathology services.

Catalent is rapidly scaling up its manufacturing capacity in Bloomington to enable production of a SARS-CoV-2 vaccine candidate that is currently being by developed by Janssen Pharmaceuticals, a subsidiary of Johnson & Johnson. The collaboration involves joint investment from Catalent and Janssen to enable large-scale commercial manufacturing by January of 2021, with segregated cGMP production lines operating 24/7 to create approximately a billion doses.

POINT Biopharma, a clinical-stage pharmaceutical company based in Canada, is establishing its first U.S. manufacturing center in Indianapolis. The $25 million project includes the purchase and renovation of an existing 77,000-sf, food-grade structure, with additional funds to be invested in sophisticated cleanroom technologies and packaging systems. Slated for occupancy in mid-2020, the GMP facility will support the production of radioligands for POINT's innovative cancer therapies. The next-generation manufacturing center will be fully operational by 2021.

Exyte is partnering with Univercells Technologies to create modular biomanufacturing facilities to meet the increased global demand for vaccines during the SARS-CoV-2 pandemic. Exyte’s prefabricated construction system, ExyCell, is paired with Univercells’ NevoLine biomanufacturing platform which features the scale-X™ fixed-bed bioreactor at its core.

Erlab, a leading provider of air filtration solutions, is presenting a webinar on the mitigation of chemical risks in the laboratory at 10:00 AM BST on May 29, 2020. The one-and-a-half hour session will explore strategies for treating chemical risks at the source to enhance occupant safety and promote operational efficiency.

Visit GoToWebinar to register.

The webinar is also being offered in Spanish, Polish, French, and Maghreb French on separate days:

Medicago is building a 646,000-sf vaccine manufacturing complex in Quebec City, Canada. Designed by NFOE, the facility will support the production of approximately 50 million doses of recombinant quadrivalent influenza vaccine per year. The project has a construction cost of CAD$143 million and is expected to be fully operational in 2023.

Medicago is currently developing a vaccine for SARS-CoV-2 which has successfully induced a positive antibody response in mouse models. Human clinical trials are expected to begin in summer of 2020.