The University of Washington’s new multi-species vivarium and animal program consolidation overcomes the challenges of combining two distinct research facilities and achieves goals of flexibility, efficient operating procedures, improved animal and personnel welfare, and a sustainable financial model—thanks to the early involvement of all affected parties, detailed team-based planning, and mockups.
The University of Delaware celebrated the opening of the newly renovated Lasher Laboratory in April of 2015. The BSL-2 facility is located in the Elbert N. and Ann V. Carvel Research and Education Center in Georgetown and supports research on the detection and diagnosis of avian diseases including avian influenza. Supported by $4 million in state funding, the project was completed in December of 2014 and included new MEP, fire, and life safety systems as well as significant improvements to the building envelope.
Walter Reed Army Institute of Research is planning to renovate a 67,000-sf animal research facility in Silver Spring, Md. Constructed in 1972 to provide biomedical laboratories and vivarium space for large and small animals, Building 511 will be extensively upgraded with new electrical, plumbing, HVAC, and building automation systems. New wall, floor, and ceiling finishes will be installed as well as vibration mitigation technologies for specialized research equipment.
The Jackson Laboratory (JAX) is planning a $75 million mouse production facility in Ellsworth, Maine. The project involves the complete renovation of an existing 143,000-sf building to create advanced vivarium space for the breeding and housing of mice for genetic research. The facility will consolidate all of JAX’s East Coast production operations in a single location, enabling the company’s Bar Harbor campus to provide additional research, education, and conference space.
The University of Nebraska broke ground in late April of 2015 on a $45.5 million veterinary diagnostic laboratory in Lincoln. Located on the Nebraska Innovation Campus, the 65,000-sf facility will provide labs for diagnostic testing, animal science, and medical research. The project architect is RDG Planning and Design of Omaha. Completion is expected in 2017.
The University of Washington is building the $123.5 million Animal Research and Care Facility in Seattle. Housing the Department of Comparative Medicine, the 83,000-sf subterranean structure will accommodate rodents, pigs, dogs, and non-human primates. Comprising two floors of approximately 40,000 sf each, the facility will provide labs, procedure rooms, imaging suites, cage and equipment wash, storage, and support. Construction began in early 2015 and occupancy is expected in August of 2017.
Minerals research firm Mintek opened a cleanroom and biocontainment laboratory in April of 2015 in Johannesburg. Supported by $2.4 million in funding from South Africa's Department of Science and Technology, the project includes an ISO 5 cleanroom and a BSL-3 suite to accommodate the development of advanced diagnostic technologies for diseases such as malaria, tuberculosis, and HIV. The facilities feature sophisticated controls for the regulation of temperature, pressure, moisture, and airborne particles.
University College London has awarded Graham Construction a $25 million contract to renovate the existing Courtauld Building to create a biomedical research facility. The project will house the Medical Research Council's Prion Unit and will accommodate the study of dementia, Alzheimer’s, and Creutzfeldt-Jakob disease.
A new animal facility at the University of Massachusetts Medical School features more efficient cage handling and cleaning, interstitial catwalks for maintenance, and a dual-corridor layout that minimizes contamination, all of which are best practices for decision-making and design, according to Jerry Silverman, director of the university’s Department of Animal Medicine, and laboratory/animal facility planner Josh Meyer. The Albert Sherman Center, the third such facility to be opened on the campus, contains several of these improvements over its predecessors.
Nanotherapeutics is building the $135 million Advanced Development and Manufacturing Center in Alachua, Fla. Designed by RS&H, the 165,000-sf project will support vaccine development and production utilizing advanced biomanufacturing technologies. Ground was broken on the facility in October of 2013 and completion is expected by 2016. Nanotherapeutics is contracted to the Department of Defense to develop medical countermeasures to chemical and biological threats as well as infectious disease outbreaks.
Researchers at the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID) have completed a study of a therapeutic candidate for the Marburg virus in a BSL-4 research facility in Fort Belvoir, Va. The study was conducted entirely under Good Laboratory Practices (GLP) conditions, setting a precedent for GLP testing of medical products for BSL-4 pathogens. This may facilitate rapid evaluation and licensing by the Food and Drug Administration (FDA).
The National Institute of Cholera and Enteric Diseases is planning to build a $2.5 million viral diagnostic and research laboratory (VDRL) in Kolkata. Sited on a 10,000-sf area of land, the BSL-3 facility will support the detection of emerging infectious diseases as well as accommodating research on virology and immunology. The project is one of 10 regional laboratories that will be constructed in India to ensure rapid response to viral outbreaks and epidemics.
In addition to massive grain processing and storage facilities, Kansas State University’s O.H. Kruse Feed Technology Innovation Center also contains a 1,200-sf BSL-2 lab for studying food-borne pathogens. The three-story high-bay Cargill Feed Safety Research Center (FSRC) is the only facility in the United States approved for feed-related research involving such pathogenic agents as Salmonella and E. coli. Previously, the University was not permitted to intentionally contaminate livestock feed with live pathogens because of the safety requirements.
The research infrastructure department at the Biodesign Institute, Arizona State University’s showcase research center, employs a dedicated facilities service organization with considerable in-house expertise, and granular benchmarking tools that track utilities and facilities costs in multiple categories of lab space, from LEED-certified green building features to general wet labs to secure ABSL-3 labs with a select agent program. In a state-sponsored research environment, where operating costs can go as high as $170 per net sf, optimizing building efficiency is critical.
Texas Tech University dedicated the 1,600-sf Biological Threat Research Laboratory in Lubbock in January of 2014. The BSL-3 facility supports basic and applied research on biological pathogens and toxins. Construction began on the $2.4 million project in September of 2012 and reached completion in summer of 2013.
