Animal Research

Texas Biomedical Research Institute is planning to construct the $10 million Nonhuman Primate Animal Facility in San Antonio. The 45,000-sf building will provide the Southwest National Primate Research Center with additional laboratories and animal housing environments, enabling TBRI to double its population of rhesus macaques. The United States currently faces a shortage of nonhuman primates for biomedical research, with the COVID-19 pandemic highlighting the need for animal models to test the safety and efficacy of new therapies, vaccines, and diagnostics.

Caltech dedicated the $210 million Tianqiao and Chrissy Chen Neuroscience Research Building in January of 2021 in Pasadena. Designed by SmithGroup to promote interdisciplinary collaboration, the 150,000-sf facility provides wet, dry, and computational research labs for the Division of Biology and Biological Engineering. Standing three stories above grade with two basement levels, the structure includes teaching labs, a neurotechnology lab, a 150-seat lecture hall, conference rooms, and offices for investigators and staff.

The needs and architectural considerations for a veterinary diagnostic laboratory (VDL) have evolved toward a greater focus on the value of human-centered design. At its core, the VDL’s purpose to provide diagnostic testing for infectious animal diseases remains the same: Biosafety and biosecurity are a top priority, while designs have evolved to meet today’s demands and anticipated future technological advancements. However, the visionary and technological advancements of recent decades have also resulted in an increased focus on designing with efficiency and quality of workplace in mind.

The most-read Tradeline articles in 2020 reflect how the industry has responded to the COVID-19 crisis with flexibility and adaptability. From virtual site visits and virus-mitigating HVAC solutions to forward-looking models for office work, research programs, and higher education, readers learned about the innovative solutions that peer organizations have adopted to weather the storm and position themselves to thrive in the recovery.

The life sciences industry has become the great hope in real estate, as we face the most significant public health crisis in a century. While other industries have slowed and suffered as a result of sheltering in place and working from home, science facilities have remained operational and even have thrived in prime markets, as the industry continues to search for medical breakthroughs. The downturn in other industries has left buildings vacant. The life science market, on the other hand, continues to experience some of the lowest vacancy and highest employment rates. For life science organizations in the prime U.S. markets, there simply remains a shortage of available research-capable space. Enter the big pivot to science.

Stanford University dedicated the $210 million Biomedical Innovation Building in November of 2020 in Palo Alto, Calif. Designed by ZGF Architects with Research Facilities Design (RFD) as laboratory design consultant, the 190,439-gsf facility strategically collocates investigators with expertise in cardiovascular medicine, pediatrics, orthopaedics, immunotherapy, personalized genomics, otolaryngology, and asthma and allergy.

Iowa State University broke ground in October of 2020 on the $75 million Veterinary Diagnostic Laboratory (VDL) in Ames. Located on the campus of the College of Veterinary Medicine, the 72,540-sf structure will provide leading-edge labs and testing suites to enable the prevention, detection, and mitigation of animal diseases including avian influenza, African Swine Fever, and porcine epidemic diarrhea virus.

The University of Wisconsin-Madison opened the $57.1 million Meat Science and Animal Biologics Discovery Building in November of 2020. Designed by Potter Lawson, the 67,540-gsf facility provides the College of Agricultural and Life Sciences with leading-edge environments for research, teaching, and outreach. The two-story structure houses two technology-rich lecture halls, a shared research lab, an expansive atrium, demonstration areas, conference rooms, faculty offices, and a retail meat store.

The University of Massachusetts Medical School is planning to construct the $325 million New Education and Research Building in Worcester. Accommodating 77 principal investigators, the nine-story, 350,000-sf facility will include space for animal research as well as housing an FDA-compliant manufacturing center for clinical trial therapeutics. The project will enable UMass to increase its class sizes help meet the needs of the commonwealth and the nation for physicians, graduate nurses, life sciences researchers, and other health sciences professionals.

Facility Logix, EwingCole, and Biggins Lacy Shapiro have launched Rapid Reshore & Development (RR&D) to provide turnkey professional services to the life sciences and biopharmaceutical industries. Addressing many of the logistical challenges faced by companies developing drugs, vaccines, and medical devices, the alliance represents an evolution from transaction-driven service models to a holistic focus on client needs.

The COVID-19 pandemic has amplified the need for the research community to respond quickly to changing markets and to understand the value of laboratory spaces that are flexible, adaptable, and scalable. We’ve seen stadiums converted to makeshift hospitals, “drive-through” testing sites pop up in vacant parking lots, and testing laboratories continually ramp up production to expedite results. This quick-thinking behavior has been inspiring to witness but daunting to execute. Laboratories, by nature, are among the most complex building typologies, where the utmost importance is protecting both the health and safety of their occupants and the integrity of the research. The complexities of the resulting design can be challenging to undertake, but when faced with the extreme circumstances of a pandemic, it is possible to expedite the process with a combination of strategies.

The Bolivian National Service of Agricultural Health and Food Safety is planning to build a 201,076-sf research campus in Santa Cruz. Strengthening the country’s research and diagnosis capacity for veterinary, phytosanitary, and food safety challenges, the state-of-the-art complex will provide four laboratory buildings for animal health, plant health, food safety, and fruit fly research, as well as an administrative center.

Fujifilm Diosynth Biotechnologies broke ground in August of 2020 on the $55 million Advanced Therapies Innovation Center in College Station, Texas. Representing an expansion of Fujifilm's cGMP manufacturing campus, the 60,000-sf facility will feature dedicated labs for process development and innovation. Research environments with BSL-2 capabilities will integrate advanced technologies for upstream, downstream, and analytical development.

Nagasaki University is planning to build a BSL-4 laboratory for SARS-CoV-2 research. The biocontainment facility will be located in an eight-story, 43,000-sf building providing specialized environments for the detection, study, and mitigation of infectious diseases. A dedicated area will accommodate novel coronavirus research. The Japanese government is expected to award $9.5 million in funding for fiscal year 2021 towards the construction of the project, which will also support training programs and the development of human resources.

Cleveland Clinic Florida opened the 107,000-sf Florida Research & Innovation Center in July of 2020 in Port St. Lucie. Accelerating the translation of medical discoveries into innovative therapeutics for clinical treatment, the facility will provide leading-edge laboratories for research programs in immuno-oncology and infectious diseases, such as Zika virus and SARS-CoV-2. The center includes BSL-3 biocontainment suites, administrative offices, meeting rooms, and an area for training programs.