Research and Development

The new Research Building IV (RB4) at Nationwide Children’s Hospital (NCH) in Columbus, Ohio, provides an ideal environment for productivity, collaboration, and flexibility by using a space policy to maximize the efficient use of labs and ancillary spaces; a neighborhood floor plan; and shared resources. The 290,000-sf building, which opened in May 2023 as part of NCH’s Abigail Wexner Research Institute (AWRI), aligns with the hospital’s “one team” culture by providing opportunities for scientists to collaborate, propelling pediatric research forward and closing the gap between lab research and bedside care.

Brandywine Realty Trust has completed construction on 3151 Market Street, a dynamic innovation facility in the heart of Philadelphia’s life sciences cluster. Designed by Gensler, the 472,000-sf tower offers purpose-built offices and customizable laboratories with options for chemical and biological use, GMP production, and vivarium operations. Collaboration and knowledge exchange are enhanced by an advanced conference center and a café, complemented by private terraces and green spaces to amplify employee productivity.

The Medical College of Wisconsin is constructing the $153 million Center for Cancer Discovery on the Milwaukee Regional Medical Center campus. Centralizing the university’s cancer research programs under one roof, this dynamic hub will catalyze discoveries in cancer biology, expand clinical trials, and create groundbreaking treatments for patients. 

Sciontec is planning to construct Hemisphere, a £156 million laboratory and office development in Liverpool, U.K. Strategically sited in the city’s Knowledge Quarter, the complex will include two eight-story structures offering a total of 216,861 nsf. Designed by AHR to foster workplace wellbeing and productivity, this nexus of discovery will also include a central biophilic plaza, interior greenhouses, showers, and a cycle hub.

Roche announced the launch of the Roche Genentech Innovation Center in March of 2025 on Harvard’s Enterprise Research Campus in Allston. With an initial lease of 30,000 sf of lab space in the first phase of construction, Roche intends to expand their R&D presence to eventually accommodate 500 employees. The initiative will bring together cardiovascular, renal, and metabolism experts with data science and AI specialists to accelerate innovation in drug discovery and development.

Cleveland Clinic is constructing the $1.1 billion Neurological Institute in Cleveland, Ohio. The 1.2 million-sf translational research facility will consolidate 15 separate centers to catalyze interdisciplinary synergies and improve patient outcomes. Spanning fourteen stories, the state-of-the-art hospital will offer a comprehensive array of services such as neuro-simulation training, infusion therapy, neurodiagnostics, brain mapping suites, imaging, and digitized patient evaluations.

Rice University opened the Rice Nexus in February of 2025 in Houston's Midtown neighborhood. Spanning 10,000 sf across two floors, the university’s flagship innovation hub is based in the Ion building to drive entrepreneurship and commercialization in association with industry partners. Tramonte Design Studio's vision for the Rice Nexus created labs for advanced tech development and free office space for early-stage startups, as well as showcasing faculty and student inventions.

The 2024 SEFA Lab of the Year was awarded to the new Roche Pharma Research and Early Development (pRED) Center in Basel, Switzerland, that opened in September 2024 as a state-of-the-art research center dedicated to the discovery and development of groundbreaking drugs. The pRED Center exemplifies the future of transformative research by fostering innovation and collaboration, and embodying Roche’s commitment to advancing global healthcare and delivering life-changing treatments. 

An evolution of the equipment and technology researchers need is transforming ordinary labs into facilities that deserve to be called next-generation or future-ready. Significant changes in space utilization and lab planning and design are driven by increased automation and robotics, the incorporation of manufacturing, enhanced information technology with an emphasis on data collection, ever-evolving technologies, developer core/shell fit-outs, hybrid work patterns, and different approaches to project delivery and construction. 

The Brazilian Center for Research in Energy and Materials (Centro Nacional de Pesquisa em Energia e Materiais) is constructing Orion, a BSL-4 laboratory complex in Campinas. Enabling the detection, study, and mitigation of pathogens and infectious disease agents, the USD185 million project will reinforce national sovereignty in response to current and future health crises and promote collaboration with the global scientific community.

Moderna completed construction on a £150 million complex in the United Kingdom for the discovery and production of mRNA vaccines and therapeutics for COVID-19 and emerging respiratory health threats. Located on the Harwell Campus in Oxfordshire, the Moderna Innovation and Technology Centre (MITC) comprises two 145,000-sf buildings for research, development, and manufacturing.

Johns Hopkins University is planning to construct a 476,572-sf facility for the Data Science and AI Institute (DSAI) on the Homewood Campus in Baltimore. Designed by ZGF, this global hub for research and discovery will bring together experts in artificial intelligence, machine learning, data science and translation, applied mathematics, and computer science and engineering.

BioMed Realty is constructing a 637,000-sf life sciences facility in Cambridge for Takeda Pharmaceuticals. Designed by CBT Architects, the 16-story structure will provide advanced lab and office environments to accelerate the creation of innovative therapies and vaccines. Featuring flexible spaces to optimize in-person interaction and connection in a hybrid working model, the leased building furthers Takeda’s goal of unifying their Global R&D Center in Kendall Square.

Ohio University began construction in January of 2025 on the $75 million Heritage Translational Research Center (HTRC) in Athens. Designed by Perkins&Will and DesignGroup, the 80,000-sf facility will consolidate laboratories and operations currently dispersed across campus, creating a collaborative ecosystem for clinical innovation. The four-story structure will provide bench space for translational biomedical research, as well as labs and support spaces for population health and clinical research.

The University of Maryland, Baltimore opened a 250,000-sf innovation center in January of 2024 to drive biomedical advances and accelerate the discovery of new health solutions. Developed and operated by Wexford Science + Technology, 4MLK serves as the gateway to the UM BioPark and will offer leasable space for life science and technology companies.